Histone 3 anticorps (H3K36me3)
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- Antigène Voir toutes Histone 3 (H3) Anticorps
- Histone 3 (H3)
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Épitope
- H3K36me3
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Histone 3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC)
- Specificité
- Tri-Methyl-Histone H3 (Lys36)/H3K36me3 Antibody detects endogenous levels of Tri-Methyl-Histone H3 only when methylated at Lys36.
- Homologie
- Horse,Sheep,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthetic methylated peptide derived from human Tri-Methyl-Histone H3 around the methylation site of Lys36.
- Isotype
- IgG
- Top Product
- Discover our top product H3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IF/ICC 1:50-1:200, CHIP 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion." dans: Scientific reports, Vol. 7, Issue 1, pp. 3568, (2017) (PubMed).
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EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion." dans: Scientific reports, Vol. 7, Issue 1, pp. 3568, (2017) (PubMed).
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- Antigène
- Histone 3 (H3)
- Autre désignation
- HIST3H3 (H3 Produits)
- Synonymes
- anticorps H-3, anticorps histocompatibility 3, anticorps H3
- Sujet
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST3H3
- Poids moléculaire
- 15kDa
- ID gène
- 8290
- UniProt
- Q16695
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