WASF2 anticorps (Internal Region)

N° du produit ABIN6280913

Détail du produit anti-WASF2 anticorps

Antigène: WASF2 (WAS Protein Family, Member 2 (WASF2))

Épitope: AA 110-190, Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WASF2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: WAVE2 is a protein encoded by the WASF2 gene which is approximately 54,2 kDa. WAVE2 is localised to the cytoplasm and is involved in regulation of actin dynamics for phagocytic cup formation, innate immune system, signalling by Rho GTPases and RET signalling. It is a downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton and is expressed in all tissues. Mutations in the WASF2 gene may result in Wiskott-Aldrich syndrome and depression. STJ96263 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of WAVE2 protein.

Specificité: WAVE2 Polyclonal Antibody detects endogenous levels of WAVE2 protein.

Attributs du produit: Rabbit polyclonal to WAVE2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human WAVE2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000

Commentaires:

Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur WASF2

Antigène: WASF2 (WAS Protein Family, Member 2 (WASF2))

Autre désignation: WAVE2 (WASF2 Produits)

Synonymes: anticorps zgc:56010, anticorps WASF2, anticorps scar2, anticorps wave2, anticorps IMD2, anticorps SCAR2, anticorps WASF4, anticorps WAVE2, anticorps dJ393P12.2, anticorps AW742646, anticorps D4Ertd13e, anticorps WAS protein family, member 2, anticorps WAS protein family member 2, anticorps WAS protein family member 2 L homeolog, anticorps wasf2, anticorps WASF2, anticorps wasf2.L, anticorps Wasf2

Poids moléculaire: 55 kDa

ID gène: 10163

UniProt: Q9Y6W5

Pathways: Signalisation RTK