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CD63 anticorps (Internal Region)

CD63 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6281100
  • Antigène Voir toutes CD63 Anticorps
    CD63
    Épitope
    • 12
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-170, Internal Region
    Reactivité
    • 128
    • 51
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 78
    • 60
    • 7
    • 3
    Lapin
    Clonalité
    • 100
    • 46
    • 2
    Polyclonal
    Conjugué
    • 71
    • 12
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD63 est non-conjugé
    Application
    • 93
    • 64
    • 51
    • 45
    • 36
    • 28
    • 26
    • 18
    • 16
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    CD63 is a protein encoded by the CD63 gene which is approximately 25,6 kDa. CD63 is localised to the cell membrane. It is involved in response to elevated platelet cytosolic Ca2+, the innate immune system and adhesion. This protein falls under the tetraspanin family. Most of these members are characterized by the presence of four hydrophobic domains. It is a cell surface glycoprotein that is known to complex with integrins and may function as a blood platelet activation marker. It also mediates signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD63 is expressed in skin, lung, blood, liver and muscle. Mutations in the CD63 gene may result in mast cell disease. STJ96890 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CD63 protein.
    Specificité
    CD63 Polyclonal Antibody detects endogenous levels of CD63 protein.
    Attributs du produit
    Rabbit polyclonal to CD63.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    Synthesized peptide derived from human CD63.
    Isotype
    IgG
    Top Product
    Discover our top product CD63 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    IHC-P 1:100-1:300
    ELISA 1:20000
    Commentaires

    Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Antigène
    CD63
    Autre désignation
    CD63 (CD63 Produits)
    Synonymes
    anticorps C75951, anticorps ME491, anticorps Tspan30, anticorps LAMP-3, anticorps MLA1, anticorps OMA81H, anticorps TSPAN30, anticorps TSP29FA, anticorps CD63 antigen, anticorps CD63 molecule, anticorps Cd63 molecule, anticorps Cd63, anticorps CD63
    ID gène
    967
    UniProt
    P08962
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