CD63 anticorps (Internal Region)
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- Antigène Voir toutes CD63 Anticorps
- CD63
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Épitope
- AA 121-170, Internal Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CD63 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- CD63 is a protein encoded by the CD63 gene which is approximately 25,6 kDa. CD63 is localised to the cell membrane. It is involved in response to elevated platelet cytosolic Ca2+, the innate immune system and adhesion. This protein falls under the tetraspanin family. Most of these members are characterized by the presence of four hydrophobic domains. It is a cell surface glycoprotein that is known to complex with integrins and may function as a blood platelet activation marker. It also mediates signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD63 is expressed in skin, lung, blood, liver and muscle. Mutations in the CD63 gene may result in mast cell disease. STJ96890 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CD63 protein.
- Specificité
- CD63 Polyclonal Antibody detects endogenous levels of CD63 protein.
- Attributs du produit
- Rabbit polyclonal to CD63.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from human CD63.
- Isotype
- IgG
- Top Product
- Discover our top product CD63 Anticorps primaire
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- Indications d'application
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WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000 - Commentaires
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Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Antigène
- CD63
- Autre désignation
- CD63 (CD63 Produits)
- Synonymes
- anticorps C75951, anticorps ME491, anticorps Tspan30, anticorps LAMP-3, anticorps MLA1, anticorps OMA81H, anticorps TSPAN30, anticorps TSP29FA, anticorps CD63 antigen, anticorps CD63 molecule, anticorps Cd63 molecule, anticorps Cd63, anticorps CD63
- ID gène
- 967
- UniProt
- P08962
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