PPP1CA anticorps (pThr320)

N° du produit ABIN6282675

Détail du produit anti-PPP1CA anticorps

Antigène: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Épitope: AA 260-340, pThr320

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1CA est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: PP1α is a protein encoded by the PPP1CA gene which is approximately 37,5 kDa. PP1α is localised to the cytoplasm and nucleus. It is involved in vascular smooth muscle contraction, regulation of lipid metabolism and insulin signalling-generic cascades. It is one of the three catalytic subunits of protein phosphatase 1. It is an enzyme that catalyses the removal of phosphate groups from serine and/or threonine residues by hydrolysis of phosphoric acid monoesters. They oppose the action of kinases and phosphorylases and are involved in signal transduction. PP1α is expressed in the lung, muscle, blood, pancreas and liver. Increased activity of this protein has been observed in the end stage of heart failure. STJ91134 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous PP1α protein which only binds about T320 when T320 is phosphorylated.

Specificité: Phospho-PP1α (T320) Polyclonal Antibody detects endogenous levels of PP1α protein only when phosphorylated at T320.

Attributs du produit: Rabbit polyclonal to Phospho-PP1α (T320).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human PP1alpha around the phosphorylation site of T320.

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300
ELISA 1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur PPP1CA

Antigène: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Autre désignation: PP1alpha (PPP1CA Produits)

Synonymes: anticorps PP-1A, anticorps PP1A, anticorps PP1alpha, anticorps PPP1A, anticorps Ppp1c, anticorps dism2, anticorps ppp1a, anticorps wu:fc04c08, anticorps wu:fc09b07, anticorps wu:fc30g11, anticorps wu:fe05h08, anticorps zgc:85729, anticorps Ppp1ca, anticorps fb18b03, anticorps fd20h04, anticorps wu:fb18b03, anticorps wu:fd20h04, anticorps wu:fl22a03, anticorps zgc:55744, anticorps zgc:76940, anticorps protein phosphatase 1 catalytic subunit alpha, anticorps protein phosphatase 1, catalytic subunit, alpha isoform, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme a, anticorps protein phosphatase 1, catalytic subunit, alpha isozyme b, anticorps PPP1CA, anticorps Ppp1ca, anticorps ppp1ca.L, anticorps ppp1ca, anticorps ppp1caa, anticorps ppp1cab

Poids moléculaire: 37 kDa

ID gène: 5499

UniProt: P62136

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism