VCP anticorps (AA 290-370)

N° du produit ABIN6282843

Détail du produit anti-VCP anticorps

Antigène: VCP (Valosin Containing Protein (VCP))

Épitope: AA 290-370

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VCP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: VCP is a protein encoded by the VCP gene which is approximately 89,3 kDa. VCP is localised to the cytoplasm, endoplasmic reticulum and nucleus. It is involved in CDK-mediated phosphorylation and removal of Cdc6, the innate immune system, the cellular response to heat stress and the HIV life cycle. It is a structural protein that associates with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. VCP is expressed in the nervous system, lung, liver, blood and skin. Mutations in the VCP gene result in inclusion body myopathy with early-onset Paget and Charcot-Marie-tooth disease type 2. STJ96231 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope specific immunogen. This polyclonal antibody detects endogenous levels of VCP protein.

Specificité: VCP Polyclonal Antibody detects endogenous levels of VCP protein.

Attributs du produit: Rabbit polyclonal to VCP.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human VCP around the non-phosphorylation site of S352.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur VCP

Antigène: VCP (Valosin Containing Protein (VCP))

Autre désignation: VCP (VCP Produits)

Synonymes: anticorps ALS14, anticorps IBMPFD, anticorps TERA, anticorps p97, anticorps CDC48, anticorps wu:fd16d05, anticorps wu:fj63d11, anticorps p93, anticorps 3110001E05, anticorps p97/VCP, anticorps 22.26, anticorps 7.12, anticorps Apple, anticorps BcDNA.GM02885, anticorps BcDNA:GM02885, anticorps CG2331, anticorps DmTER94, anticorps Dmel\CG2331, anticorps I, anticorps Ter94, anticorps Tera, anticorps VCP, anticorps VCP ATPase, anticorps VCP/p97, anticorps Vcp, anticorps anon-WO2004063362.65, anticorps anon-WO2004063362.67, anticorps cdc48, anticorps dTERA, anticorps dVCP, anticorps dmTERA, anticorps dvcp, anticorps l(2)03775, anticorps l(2)46CFf, anticorps l(2)46CFs, anticorps l(2)46Ch, anticorps pTER94, anticorps ter94, anticorps vcp, anticorps FANCG, anticorps valosin containing protein, anticorps valosin containing protein S homeolog, anticorps valosin-containing protein, anticorps CG2331 gene product from transcript CG2331-RA, anticorps zgc:136908, anticorps transitional endoplasmic reticulum ATPase, anticorps VCP, anticorps vcp.S, anticorps vcp, anticorps Vcp, anticorps Bm1_56585, anticorps LOC100136246, anticorps TER94, anticorps zgc:136908, anticorps LOC101109680

Poids moléculaire: 85 kDa

ID gène: 7415

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway