VEGFR2/CD309 anticorps (AA 890-970)
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- Antigène Voir toutes VEGFR2/CD309 (VEGFR2) Anticorps
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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Épitope
- AA 890-970
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp VEGFR2/CD309 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Flk-1 is a protein encoded by the KDR gene which is approximately 151,5 kDa. Flk-1 isoform 1 is localised to the cell membrane and isoform 2 and 3 are secreted. It is involved in apoptotic pathways, the GPCR pathway, ERK signalling and the CREB pathway. This receptor is one of two type III receptor tyrosine kinase that functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor. Flk-1 is widely expressed in human tissues including the cornea. Mutations in the KDR gene may result in hemangioma. STJ93088 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Flk-1 protein.
- Specificité
- Flk-1 Polyclonal Antibody detects endogenous levels of Flk-1 protein.
- Attributs du produit
- Rabbit polyclonal to Flk-1.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from human Flk-1 around the non-phosphorylation site of Y951.
- Isotype
- IgG
- Top Product
- Discover our top product VEGFR2 Anticorps primaire
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- Indications d'application
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WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000 - Commentaires
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Detected in cornea (at protein level). Widely expressed.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Antigène
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
- Autre désignation
- Flk-1 (VEGFR2 Produits)
- Synonymes
- anticorps CD309, anticorps FLK1, anticorps VEGFR, anticorps VEGFR2, anticorps 6130401C07, anticorps Flk-1, anticorps Flk1, anticorps Krd-1, anticorps Ly73, anticorps VEGFR-2, anticorps sVEGFR-2, anticorps Vegfr-2, anticorps FLK-1, anticorps flk-1, anticorps vegfr-2, anticorps KDR, anticorps FLK/KDR, anticorps flk1, anticorps flk1b, anticorps kdrb, anticorps si:busm1-205d10.1, anticorps si:ch211-254j6.1, anticorps si:ch211-278f21.4, anticorps wu:fc31a09, anticorps fk52c05, anticorps flk, anticorps kdr, anticorps kdra, anticorps vegfr2, anticorps vegfr4, anticorps vegr2, anticorps wu:fk52c05, anticorps kinase insert domain receptor, anticorps kinase insert domain protein receptor, anticorps vascular endothelial growth factor receptor kdr-like, anticorps kinase insert domain receptor (a type III receptor tyrosine kinase), anticorps kinase insert domain receptor like, anticorps KDR, anticorps Kdr, anticorps LOC100136647, anticorps kdr, anticorps kdrl
- Poids moléculaire
- 151 kDa
- ID gène
- 3791
- UniProt
- P35968
- Pathways
- Signalisation RTK, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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