HIF3A anticorps (Internal Region)

N° du produit ABIN6286917

Détail du produit anti-HIF3A anticorps

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIF3A est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit polyclonal to HIF-3α.

Specificité: HIF-3α Polyclonal Antibody detects endogenous levels of HIF-3α protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human HIF-3alpha.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
ELISA 1:20000

Commentaires:

Expressed in vascular cells (at protein level) . Expressed in kidney . Expressed in lung epithelial cells . Expressed in endothelial cells (venous and arterial cells from umbilical cord and aortic endothelial cells) and in vascular smooth muscle cells (aorta) . Strongly expressed in the heart, placenta, and skeletal muscle, whereas a weak expression profile was found in the lung, liver, and kidney . Expressed weakly in cell renal cell carcinoma (CC-RCC) compared to normal renal cells . Expression is down-regulated in numerous kidney tumor cells compared to non tumor kidney tissues . Isoform 2 is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas and in numerous cancer cell lines . Isoform 3 and isoform 4 are weakly expressed in heart, placenta, lung, liver, skeletal muscle and pancreas . Isoform 4 is expressed in fetal tissues, such as heart, brain, thymus, lung, liver, skeletal kidney and spleen . Isoform 3 is weakly expressed in fetal tissues, such as liver and kidney .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur HIF3A

Antigène: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Autre désignation: HIF-3alpha (HIF3A Produits)

Synonymes: anticorps HIF-3A, anticorps IPAS, anticorps MOP7, anticorps PASD7, anticorps bHLHe17, anticorps Ipas, anticorps NEPAS, anticorps Mop7, anticorps HIF3A, anticorps hypoxia inducible factor 3 alpha subunit, anticorps hypoxia inducible factor 3, alpha subunit, anticorps HIF3A, anticorps Hif3a

Poids moléculaire: 72 kDa

UniProt: Q9Y2N7

Pathways: L'effet Warburg