MME anticorps

N° du produit ABIN6288762

Détail du produit anti-MME anticorps

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MME est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: CD10 is a protein encoded by the MME gene which is approximately 85,5 kDa. CD10 is localised to the cell membrane. It is involved in the innate immune system, respiratory electron transport, peptide hormone metabolism and hematopoietic cell lineage. It is a common acute lymphocytic leukaemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukaemia. It acts as a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon and enkephalins. CD10 is expressed in the kidney, the cells of the nervous system, liver, blood and bone marrow. Mutations in the MME gene may result in Charcot-Marie-Tooth disease. STJ96974 was developed from clone 5B8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous CD10 proteins.

Specificité: The antibody detects endogenous CD10 proteins.

Attributs du produit: Mouse monoclonal to CD10.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogène: Synthetic Peptide

Clone: 5B8

Isotype: IgG1

Information d'application

Indications d'application: IHC 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur MME

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: CD10 (MME Produits)

Synonymes: anticorps CALLA, anticorps CD10, anticorps NEP, anticorps SFE, anticorps 6030454K05Rik, anticorps C85356, anticorps Nep, anticorps neprilysin, anticorps membrane metalloendopeptidase, anticorps membrane metallo endopeptidase, anticorps membrane metallo-endopeptidase, anticorps MME, anticorps Mme

Classe de substances: Chemical

ID gène: 4311

UniProt: P08473

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration