GDF5 anticorps

N° du produit ABIN6290098

Détail du produit anti-GDF5 anticorps

Antigène: GDF5 (Growth Differentiation Factor 5 (GDF5))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF5 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human GDF5

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Predominantly expressed in long bones during embryonic development, Expressed in monocytes (at protein level)

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur GDF5

Antigène: GDF5 (Growth Differentiation Factor 5 (GDF5))

Autre désignation: GDF5 (GDF5 Produits)

Synonymes: anticorps CDMP1, anticorps gdf, anticorps gdf-5, anticorps GDF5, anticorps BDA1C, anticorps BMP14, anticorps LAP4, anticorps OS5, anticorps SYM1B, anticorps SYNS2, anticorps Cdmp-1, anticorps bp, anticorps brp, anticorps Cdmp1, anticorps growth differentiation factor 5 L homeolog, anticorps growth differentiation factor 5, anticorps gdf5.L, anticorps GDF5, anticorps Gdf5

Sujet: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.

Poids moléculaire: 55.411 kDa

ID gène: 8200

UniProt: P43026