WISP3 anticorps

N° du produit ABIN6291067

Détail du produit anti-WISP3 anticorps

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WISP3 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human WISP3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Predominant expression in adult kidney and testis and fetal kidney, Weaker expression found in placenta, ovary, prostate and small intestine, Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur WISP3

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Autre désignation: WISP3 (WISP3 Produits)

Synonymes: anticorps CCN6, anticorps LIBC, anticorps PPAC, anticorps PPD, anticorps ENSMUSG00000062074, anticorps Gm735, anticorps WISP-3, anticorps RGD1564120, anticorps WISP3, anticorps si:dkey-119m7.6, anticorps WNT1 inducible signaling pathway protein 3, anticorps WISP3, anticorps Wisp3, anticorps wisp3

Sujet: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 39.293 kDa

ID gène: 8838

UniProt: O95389

Pathways: Signalisation WNT, Growth Factor Binding