CXCR7 anticorps

N° du produit ABIN6291935

Détail du produit anti-CXCR7 anticorps

Antigène: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR7 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human ACKR3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Expressed in monocytes, basophils, B-cells, umbilical vein endothelial cells (HUVEC) and B-lymphoblastoid cells, Lower expression detected in CD4+ T-lymphocytes and natural killer cells, In the brain, detected in endothelial cells and capillaries, and in mature neurons of the frontal cortex and hippocampus, Expressed in tubular formation in the kidney, Highly expressed in astroglial tumor endothelial, microglial and glioma cells, Expressed at low levels in normal CD34+ progenitor cells, but at very high levels in several myeloid malignant cell lines, Expressed in breast carcinomas but not in normal breast tissue (at protein level)

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur CXCR7

Antigène: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Autre désignation: ACKR3 (CXCR7 Produits)

Synonymes: anticorps CMKOR1, anticorps CXC-R7, anticorps CXCR-7, anticorps CXCR7, anticorps GPR159, anticorps RDC-1, anticorps RDC1, anticorps AW541270, anticorps Cmkor1, anticorps Cxcr7, anticorps Rdc1, anticorps ackr3, anticorps cxcr7, anticorps rdc1, anticorps xcxcr7, anticorps atypical chemokine receptor 3, anticorps ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74, anticorps atypical chemokine receptor 3 L homeolog, anticorps ACKR3, anticorps MmrVgp88, anticorps Ackr3, anticorps ackr3.L

Sujet: This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

Poids moléculaire: 41.493 kDa

ID gène: 57007

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling