PHLDA2 anticorps

N° du produit ABIN6292224

Détail du produit anti-PHLDA2 anticorps

Antigène: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHLDA2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant protein of human PHLDA2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Commentaires:

Expressed in placenta and adult prostate gland, In placenta, it is present in all cells of the villous cytotrophoblast, The protein is absent in cells from hydatidiform moles, Hydatidiform mole is a gestation characterized by abnormal development of both fetus and trophoblast, The majority of hydatidiform moles are associated with an excess of paternal to maternal genomes and are likely to result from the abnormal expression of imprinted genes (at protein level), Expressed at low levels in adult liver and lung, and fetal liver, Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur PHLDA2

Antigène: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Autre désignation: PHLDA2 (PHLDA2 Produits)

Synonymes: anticorps PHLDA2, anticorps ipl, anticorps phlda2, anticorps BRW1C, anticorps BWR1C, anticorps HLDA2, anticorps IPL, anticorps TSSC3, anticorps Ipl, anticorps Tssc3, anticorps zgc:110459, anticorps pleckstrin homology like domain family A member 2, anticorps Pleckstrin homology-like domain family A member 2, anticorps pleckstrin homology like domain, family A, member 2, anticorps pleckstrin homology-like domain, family A, member 2, anticorps pleckstrin homology-like domain, family A, member 2 L homeolog, anticorps PHLDA2, anticorps phla2, anticorps Phlda2, anticorps phlda2.L, anticorps phlda2

Sujet: This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.

Poids moléculaire: 17.092 kDa

ID gène: 7262

UniProt: Q53GA4

Pathways: Regulation of Carbohydrate Metabolic Process