STAT2 anticorps (Biotin)

N° du produit ABIN6297844

Détail du produit anti-STAT2 anticorps (Biotin)

Antigène: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAT2 est conjugé à/à la Biotin

Application: ELISA

Fonction: Rabbit anti-Human Phosphorylated STAT2 Antibody [+Biotin],

Immunogène: This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen. The IgG fraction was purified by Protein A affinity chromatography.

Information d'application

Indications d'application: ELISA (recommended work dilution= 1:320,000)

Restrictions: For Research Use only

Stockage

Reconstitution: Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution . Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: -20°C

Détails sur STAT2

Antigène: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Autre désignation: Signal transducer and activator of transcription 2 (STAT2 Produits)

Synonymes: anticorps wu:fj84d07, anticorps p113, anticorps stat2, anticorps 1600010G07Rik, anticorps AW496480, anticorps ISGF-3, anticorps P113, anticorps STAT113, anticorps signal transducer and activator of transcription 2, anticorps AGAP000099-PA, anticorps stat2, anticorps STAT2, anticorps Stat2

Sujet:

Target Description: Signal transducer and activator of transcription 2  is a  protein  that in humans is encoded by the STAT2  gene.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (IRF9), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.STAT2-PY is the phosphorylated form of STAT2 protein.

Gene Symbol: STAT2

ID gène: 6773

UniProt: P52630

Pathways: Signalistation JAK/STAT, Hepatitis C, CXCR4-mediated Signaling Events