beta-2 Microglobulin anticorps

N° du produit ABIN636142

Détail du produit anti-beta-2 Microglobulin anticorps

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp beta-2 Microglobulin est non-conjugé

Application: Veuillez nous consulter SVP

Specificité: Beta 2 Microglobulin antibody was raised against Human Beta-2-Microglobulin.

Purification: Affinity purified

Pureté: > 95 % pure

Stérilité: Filtered

Immunogène: Human beta-2-microglobulin
Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian.

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Clear, colorless liquid, 0.2 µm filtered, containing 10 mM Sodium Phosphate, 0.15 M Sodium Chloride and 0.05 % (w/v) Sodium Azide. Protease/IgG free.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8 °C.

Détails sur beta-2 Microglobulin

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Autre désignation: beta 2 Microglobulin (B2M Produits)

Synonymes: anticorps Ly-m11, anticorps beta2-m, anticorps beta2m, anticorps bwm, anticorps wu:fa94c05, anticorps wu:fb10a09, anticorps b2m-W01, anticorps b2m-W03, anticorps b2m-Z01, anticorps b2m-Z02, anticorps b2m-Z03, anticorps B2M, anticorps b2m, anticorps B2MG, anticorps wu:fb66f11, anticorps wu:fj01f08, anticorps zgc:64161, anticorps b-2-m, anticorps beta-2-microglobulin, anticorps beta-2 microglobulin, anticorps beta-2-microglobulin S homeolog, anticorps beta-2-microglobulin, like, anticorps B2M, anticorps B2m, anticorps b2m, anticorps b2m.S, anticorps b2ml

Sujet: Beta 2 Microglobulin is a low molecular weight protein with sequence homology to immunoglobulins. As a portion of the HLA complex this protein is an important cell-surface structure. Under normal conditions Beta 2 Microglobulin is synthesized and shed by many cells, particularly lymphocytes, and is detectable in the circulation of normal individuals. Because of its small size it is normally filtered readily at the glomerulus and is catabolized by proximal tubular cells of the kidney. Impaired renal function and hyperproduction of Beta 2 Microglobulin are both associated with increased serum levels. A function for Beta 2 Microglobulin as a modulator of lymphocyte surface and as a potential regulator of the immune system is proposed.

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process