IL1RN anticorps

N° du produit ABIN636640

Détail du produit anti-IL1RN anticorps

Antigène: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1RN est non-conjugé

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Purified

Immunogène: IL1 RA antibody was raised in rabbit using highly pure recombinant human IL-1 A as the immunogen.

Information d'application

Indications d'application: ELISA: 0.5-2 µg/mL, Inhibition: 2.5-3.7 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur IL1RN

Antigène: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Autre désignation: IL1RA (IL1RN Produits)

Synonymes: anticorps DIRA, anticorps ICIL-1RA, anticorps IL-1RN, anticorps IL-1ra, anticorps IL-1ra3, anticorps IL1F3, anticorps IL1RA, anticorps IRAP, anticorps MVCD4, anticorps IRAP1, anticorps IL1RN, anticorps IL-1RA, anticorps F630041P17Rik, anticorps interleukin 1 receptor antagonist, anticorps interleukin 1 receptor antagonist-like, anticorps IL1RN, anticorps Il1rn, anticorps IL1RNL

Sujet: Interleukin-1 receptor antagonist (IL1RA) is a naturally occurring inflammatory inhibitor protein. It inhibits the activity of IL1a and IL1beta by competitively blocking binding to their type I and type II receptors. IL1Ra is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL1Ra may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease.

Poids moléculaire: 17.2 kDa (predicted detection band MW)

Pathways: Signalisation NF-kappaB, Hormone Transport, Cancer Immune Checkpoints