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AXIN2 anticorps (C-Term)

AXIN2 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB26798 unconjugated
N° du produit ABIN2840323
  • Antigène Voir toutes AXIN2 Anticorps
    AXIN2 (Axin 2 (AXIN2))
    Épitope
    • 15
    • 14
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 816-843, C-Term
    Reactivité
    • 71
    • 53
    • 40
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 84
    • 2
    Lapin
    Clonalité
    • 75
    • 11
    Polyclonal
    Conjugué
    • 25
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AXIN2 est non-conjugé
    Application
    • 63
    • 38
    • 30
    • 14
    • 13
    • 13
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This AXIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human AXIN2.
    Clone
    RB26798
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AXIN2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    AXIN2 (Axin 2 (AXIN2))
    Autre désignation
    AXIN2 (AXIN2 Produits)
    Synonymes
    anticorps AXIL, anticorps ODCRCS, anticorps axil, anticorps wu:fb37c08, anticorps zgc:111942, anticorps axin-2, anticorps xarp, anticorps MGC81576, anticorps arp-A, anticorps axin2, anticorps Axi1, anticorps Axil, anticorps Conductin, anticorps axin 2, anticorps axin 2 (conductin, axil), anticorps axin 2 (conductin, axil) S homeolog, anticorps AXIN2, anticorps axin2, anticorps axin2.S, anticorps Axin2
    Sujet
    The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
    Poids moléculaire
    93558
    ID gène
    8313
    NCBI Accession
    NP_004646
    UniProt
    Q9Y2T1
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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