COL8a2 anticorps (C-Term)

N° du produit ABIN655804

Détail du produit anti-COL8a2 anticorps

Antigène: COL8a2 (COL8A2) (Collagen, Type VIII, alpha 2 (COL8A2))

Épitope: AA 571-599, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL8a2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This COL8A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the C-terminal region of human COL8A2.

Clone: RB31742

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-COL8a2 (ABIN655804)

Okumura, Minamiyama, Ho, Kay, Kawasaki, Tourtas, Schlötzer-Schrehardt, Kruse, Young, Quantock, Kinoshita, Koizumi: "Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 11, pp. 1291-304, (2015) (PubMed).

Détails sur COL8a2

Antigène: COL8a2 (COL8A2) (Collagen, Type VIII, alpha 2 (COL8A2))

Autre désignation: COL8A2 (COL8A2 Produits)

Synonymes: anticorps FECD, anticorps FECD1, anticorps PPCD, anticorps PPCD2, anticorps AI429819, anticorps collagen type VIII alpha 2 chain, anticorps collagen, type VIII, alpha 2, anticorps COL8A2, anticorps Col8a2

Sujet: This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.

Poids moléculaire: 67244

ID gène: 1296

NCBI Accession: NP_005193

UniProt: P25067