FGFR3 anticorps

N° du produit ABIN6566588

Détail du produit anti-FGFR3 anticorps

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR3 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human FGFR3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FGFR3

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Autre désignation: FGFR3 (FGFR3 Produits)

Synonymes: anticorps FGFR3, anticorps LOC100034114, anticorps ACH, anticorps CD333, anticorps CEK2, anticorps HSFGFR3EX, anticorps JTK4, anticorps FR3, anticorps Fgfr-3, anticorps Flg-2, anticorps HBGFR, anticorps Mfr3, anticorps sam3, anticorps fc27h01, anticorps wu:fc27h01, anticorps fibroblast growth factor receptor 3, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog, anticorps FGFR3, anticorps fgfr3.S, anticorps Fgfr3, anticorps fgfr3

Sujet:

Synonyms: ACH,CD 333,CD333,CD333 antigen,CEK 2,CEK2,FGFR 3,FGFR-3,FGFR3,FGFR3,Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism),Fibroblast growth factor receptor 3,Heparin binding growth factor receptor,HSFGFR3EX,Hydroxyaryl protein kinase,JTK 4,JTK4,MFR 3,SAM 3,Tyrosine kinase JTK 4,Tyrosine kinase JTK4,Z FGFR 3

Background: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Poids moléculaire:

Observed_MW: 115kDa

Calculated_MW: 75kDa/85kDa/87kDa/88kDa

ID gène: 2261

UniProt: P22607

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding