Nibrin anticorps

N° du produit ABIN5963855

Détail du produit anti-Nibrin anticorps

Antigène: Nibrin (NBN)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nibrin est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human NBN

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Nibrin

Antigène: Nibrin (NBN)

Autre désignation: NBN (NBN Produits)

Synonymes: anticorps NBN, anticorps AT-V1, anticorps AT-V2, anticorps ATV, anticorps NBS, anticorps NBS1, anticorps P95, anticorps Nbs1, anticorps im:6911679, anticorps zgc:194152, anticorps nibrin, anticorps NBN, anticorps nbn, anticorps Nbn

Sujet:

Synonyms: AT V1,AT V2,ATV,Cell cycle regulatory protein p95,FLJ10155,MGC87362,Nbn,NBN,NBS 1,NBS,NBS1,Nibrin,Nijmegen breakage syndrome 1 (nibrin),Nijmegen breakage syndrome,Nijmegen breakage syndrome protein 1,p95,p95 protein of the MRE11/RAD50 complex

Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Poids moléculaire:

Observed_MW: 95kDa

Calculated_MW: 84kDa

ID gène: 4683

UniProt: O60934

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response