DYNC2LI1 anticorps

N° du produit ABIN6569748

Détail du produit anti-DYNC2LI1 anticorps

Antigène: DYNC2LI1 (Dynein, Cytoplasmic 2, Light Intermediate Chain 1 (DYNC2LI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DYNC2LI1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human DYNC2LI1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DYNC2LI1

Antigène: DYNC2LI1 (Dynein, Cytoplasmic 2, Light Intermediate Chain 1 (DYNC2LI1))

Autre désignation: DYNC2LI1 (DYNC2LI1 Produits)

Synonymes: anticorps DYNC2LI1, anticorps 4933404O11Rik, anticorps CGI-60, anticorps D2lic, anticorps LIC3, anticorps mD2LIC, anticorps D2LIC, anticorps dynein cytoplasmic 2 light intermediate chain 1, anticorps DYNC2LI1, anticorps Dync2li1

Sujet:

Synonyms: CGI-60,Cytoplasmic dynein 2 light intermediate chain 1,D2LIC,DC2L1,DYNC2LI1,Dynein 2 light intermediate chain,Dynein, cytoplasmic 2, light intermediate chain 1,LIC3

Background: This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire:

Observed_MW: 38kDa

Calculated_MW: 15kDa/22kDa/37kDa/39kDa

ID gène: 51626

UniProt: Q8TCX1

Pathways: Signalisation Hedgehog