ATP7B anticorps

N° du produit ABIN5962914

Détail du produit anti-ATP7B anticorps

Antigène: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP7B est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ATP7B (NP_001230111.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATP7B

Antigène: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Autre désignation: ATP7B (ATP7B Produits)

Synonymes: anticorps PWD, anticorps WC1, anticorps WD, anticorps WND, anticorps Atp7a, anticorps tx, anticorps Hts, anticorps PINA, anticorps Wd, anticorps ATP7B, anticorps ATPase copper transporting beta, anticorps ATPase, Cu++ transporting, beta polypeptide, anticorps ATPase, Cu++ transporting, beta polypeptide (Wilson disease), anticorps copper-transporting ATPase 2, anticorps ATP7B, anticorps Atp7b, anticorps atp7b, anticorps LOC592143

Sujet: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Poids moléculaire:

Observed_MW: 150kDa

Calculated_MW: 133kDa/145kDa/155kDa/157kDa

ID gène: 540

UniProt: P35670

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process