Caspase 4 anticorps
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- Antigène Voir toutes Caspase 4 (CASP4) Anticorps
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Caspase 4 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of mouse CASP4
- Isotype
- IgG
- Top Product
- Discover our top product CASP4 Anticorps primaire
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- Indications d'application
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
- Autre désignation
- CASP4 (CASP4 Produits)
- Synonymes
- anticorps ICE(rel)II, anticorps ICEREL-II, anticorps ICH-2, anticorps Mih1/TX, anticorps TX, anticorps Casp11, anticorps CASP13, anticorps CASP1, anticorps CASP4, anticorps Caspl, anticorps ich-3, anticorps Casp4, anticorps caspase 4, anticorps caspase 4, apoptosis-related cysteine peptidase, anticorps caspase-4, anticorps CASP4, anticorps Casp4, anticorps LOC100731032
- Sujet
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Synonyms: Apoptotic cysteine protease Mih1/TX,CASP-4,CASP4,CASP4,Caspase 4 apoptosis related cysteine peptidase,Caspase-4 subunit 2,Caspase4,ICE(rel)-II,ICE(rel)II,ICEREL II,ICH2,Mih1/TX,Protease ICH-2,Protease TX,TX
Background: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
- Poids moléculaire
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Observed_MW: 43-48kDa
Calculated_MW: 13kDa/18kDa/30kDa/36kDa/43kDa
- ID gène
- 12363
- UniProt
- P70343
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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