MUS81 anticorps
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- Antigène Voir toutes MUS81 Anticorps
- MUS81 (MUS81 Endonuclease Homolog (MUS81))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MUS81 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human MUS81 (NP_079404.3).
- Isotype
- IgG
- Top Product
- Discover our top product MUS81 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- MUS81 (MUS81 Endonuclease Homolog (MUS81))
- Autre désignation
- MUS81 (MUS81 Produits)
- Synonymes
- anticorps CG3026, anticorps Dmel\\CG3026, anticorps EG:BACR7A4.16, anticorps MUS81, anticorps GB15332, anticorps ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81, anticorps ATMUS81, anticorps F6I18.220, anticorps F6I18_220, anticorps MMS AND UV SENSITIVE 81, anticorps SLX3, anticorps slx3, anticorps 1200008A18Rik, anticorps AI182501, anticorps AW045863, anticorps wu:fc26g01, anticorps zgc:66489, anticorps zgc:91801, anticorps CG3026 gene product from transcript CG3026-RA, anticorps MUS81 structure-specific endonuclease subunit, anticorps crossover junction endonuclease MUS81, anticorps Restriction endonuclease, type II-like superfamily protein, anticorps Mus81p, anticorps Holliday junction resolvase subunit Mus81, anticorps MUS81 protein, anticorps hypothetical protein, anticorps mus81, anticorps MUS81, anticorps LOC725951, anticorps Mus81, anticorps CAALFM_C600540WA
- Sujet
- This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.
- Poids moléculaire
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Observed_MW: 60kDa
Calculated_MW: 61kDa
- ID gène
- 80198
- UniProt
- Q96NY9
- Pathways
- Réparation de l'ADN
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