SIRPA anticorps

N° du produit ABIN5965376

Détail du produit anti-SIRPA anticorps

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRPA est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human SIRPA

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: SIRPA (SIRPA Produits)

Synonymes: anticorps BIT, anticorps CD172A, anticorps MFR, anticorps MYD-1, anticorps P84, anticorps PTPNS1, anticorps SHPS1, anticorps SIRP, anticorps SIRPA, anticorps SIRP-A1, anticorps SIRP-B1, anticorps AI835480, anticorps Bit, anticorps CD172a, anticorps Ptpns1, anticorps SHP-1, anticorps SHPS-1, anticorps swc3, anticorps signal regulatory protein alpha, anticorps myeloperoxidase, anticorps signal-regulatory protein alpha, anticorps tyrosine-protein phosphatase non-receptor type substrate 1, anticorps SIRPA, anticorps MPO, anticorps LOC458039, anticorps LOC100400378, anticorps LOC100590224, anticorps Sirpa

Sujet:

Synonyms: Signal regulatory protein alpha type 1,Bit,Brain Ig like molecule with tyrosine based activation motifs,Brain Ig-like molecule with tyrosine-based activation motifs,Brain immunoglobulin like molecule with tyrosine based activation motifs,CD172 antigen like family member A,CD172 antigen-like family member A,CD172a,CD172a antigen,Inhibitory receptor SHPS-1,Macrophage fusion receptor,MFR,MYD 1,Myd 1 antigen,MyD-1 antigen,p84,Protein tyrosine phosphatase non receptor type substrate 1,PTPNS1,SHP substrate 1,SHPS-1,SHPS1,SHPS1,Signal regulatory protein alpha 2,Signal regulatory protein alpha 3,Signal regulatory protein alpha,Signal regulatory protein alpha type 2,Signal-regulatory protein alpha-1,Signal-regulatory protein alpha-2,Signal-regulatory protein alpha-3,SIRP,Sirp-alpha-1,Sirp-alpha-2,Sirp-alpha-3,SIRPA,SIRPalpha,SIRPalpha1,SIRPalpha2,SIRPalpha3,Tyrosine phosphatase SHP substrate 1,Tyrosine protein phosphatase non receptor type substrate 1,Tyrosine-protein phosphatase non-receptor type substrate 1

Background: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

Poids moléculaire:

Observed_MW: 120kDa

Calculated_MW: 54kDa/55kDa

ID gène: 140885

UniProt: P78324