SCN8A anticorps

N° du produit ABIN6658134

Détail du produit anti-SCN8A anticorps

Antigène: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SCN8A est non-conjugé

Application: Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Anti-Nav1.6 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Nav1.6 from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Nav1.6 from other sources has not been determined. Ion Channels research.

Immunogène:

Immunogen: Nav1.6 Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to the intracellular interdomain loop I-II of rat Nav1.6.

Immunogen Type: Peptide

Clone: S87A-10

Isotype: IgG1

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-Nav1.6 Antibody is suitable for use in IP and IHC. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur SCN8A

Antigène: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Autre désignation: Nav1.6 (SCN8A Produits)

Synonymes: anticorps CERIII, anticorps CIAT, anticorps EIEE13, anticorps MED, anticorps NaCh6, anticorps Nav1.6, anticorps PN4, anticorps AI853486, anticorps C630029C19Rik, anticorps dmu, anticorps med, anticorps mnd-2, anticorps mnd2, anticorps nmf2, anticorps nmf335, anticorps nmf58, anticorps nur14, anticorps seal, anticorps sodium voltage-gated channel alpha subunit 8, anticorps sodium channel, voltage-gated, type VIII, alpha, anticorps SCN8A, anticorps Scn8a

Sujet:

Synonyms: Scn8A, Sodium channel protein type 8 subunit alpha, Peripheral nerve protein type 4, PN4, Sodium channel 6, NaCh6, Sodium channel protein type VIII subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.6

Background: Voltage gated sodium channels initiate action potentials in neurons. Nav1.6 subunits have been assessed to meditate resurgent and persistent sodium currents in cells with a resulting effect on repetitive firing behavior. Nav1.6 subunits have been found to activate at more negative voltages than other Nav subunits.

Gene Name: Scn8a

ID gène: 29710

NCBI Accession: NP_062139

UniProt: O88420

Pathways: Sensory Perception of Sound