PD-L1 anticorps (AA 39-191)

N° du produit ABIN6939568

Détail du produit anti-PD-L1 anticorps

Antigène: PD-L1 (CD274 (PD-L1))

Épitope: AA 39-191

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-L1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Coating (Coat)

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment of human CD274 protein (around aa 39-191) (exact sequence is proprietary)

Clone: PDL1-2743

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: Heart, Placenta, Spleen or Tonsil (IHC). Jurkat cells (IF/FACS).

Known Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/mL),Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PD-L1

Antigène: PD-L1 (CD274 (PD-L1))

Autre désignation: CD274 (PD-L1 Produits)

Synonymes: anticorps B7-H, anticorps B7H1, anticorps PD-L1, anticorps PDCD1L1, anticorps PDCD1LG1, anticorps PDL1, anticorps A530045L16Rik, anticorps B7h1, anticorps Pdcd1l1, anticorps Pdcd1lg1, anticorps Pdl1, anticorps RGD1566211, anticorps CD274 molecule, anticorps CD274 antigen, anticorps programmed cell death 1 ligand 2, anticorps CD274, anticorps Cd274, anticorps PDCD1LG2

Sujet: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Poids moléculaire: 37-50kDa

ID gène: 29126

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints