DROSHA anticorps

N° du produit ABIN6943116

Détail du produit anti-DROSHA anticorps

Antigène: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp DROSHA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human Drosha aa 1-150

Clone: 5C9

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DROSHA

Antigène: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Autre désignation: Drosha (DROSHA Produits)

Synonymes: anticorps im:7150667, anticorps zgc:158612, anticorps ETOHI2, anticorps HSA242976, anticorps RANSE3L, anticorps RN3, anticorps RNASE3L, anticorps RNASEN, anticorps 1110013A17Rik, anticorps AI874853, anticorps Etohi2, anticorps Rn3, anticorps Rnasen, anticorps RGD1307626, anticorps ribonuclease type III, nuclear, anticorps Ribonuclease 3, anticorps ribonuclease 3, anticorps drosha ribonuclease III, anticorps drosha, ribonuclease type III, anticorps rnasen, anticorps Thicy_0885, anticorps Sinme_0866, anticorps Isova_2087, anticorps Sphch_0770, anticorps DROSHA, anticorps Drosha

Sujet:

Synonyms: Ribonuclease 3, Protein Drosha, Ribonuclease III, p241, RNase III, DROSHA, RN3, RNASE3L, RNASEN.

Background: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.

ID gène: 29102

UniProt: Q9NRR4

Pathways: Regulatory RNA Pathways