IL-6 anticorps

N° du produit ABIN6963871

Cet anticorps anti-IL-6 est un anticorps Rat Monoclonal détectant IL-6 dans ELISA et ELISpot. Adapté pour Humain et Non-Human Primate. Ce Primary Antibody a été cité dans 5+ publications.

Aperçu rapide pour IL-6 anticorps (ABIN6963871)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Humain, Non-Human Primate

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 est non-conjugé

Application: ELISA, ELISpot

Clone: 13A5

Détail du produit anti-IL-6 anticorps

Specificité: Native and recombinant IL-6

Réactivité croisée (Details): The monoclonal antibody cross-reacts with IL-6 from non-human primates.

Attributs du produit: This monoclonal antibody enables specific detection of human IL-6 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human IL-6

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

ABIN6963871, ABIN7448314 and ABIN6964024 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963872 and ABIN7448315 .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-IL-6 (ABIN6963871)

Palizgir, Akhtari, Mahmoudi, Mostafaei, Rezaiemanesh, Shahram: "Curcumin reduces the expression of interleukin 1β and the production of interleukin 6 and tumor necrosis factor alpha by M1 macrophages from patients with Behcet's disease." dans: Immunopharmacology and immunotoxicology, Vol. 40, Issue 4, pp. 297-302, (2018) (PubMed).

Sui, Hogg, Wang, Frey, Yu, Xia, Venzon, McKinnon, Smedley, Gathuka, Klinman, Keele, Langermann, Liu, Franchini, Berzofsky: "Vaccine-induced myeloid cell population dampens protective immunity to SIV." dans: The Journal of clinical investigation, Vol. 124, Issue 6, pp. 2538-49, (2014) (PubMed).

Gille-Johnson, Smedman, Gudmundsdotter, Somell, Nihlmark, Paulie, Andersson, Gårdlund: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." dans: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).

Feliu, Walter, Montañez, Kunzmann, Hult, Nyström, Malkoch, Fadeel: "Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers." dans: Biomaterials, Vol. 33, Issue 7, pp. 1970-81, (2012) (PubMed).

Snyder-Cappione, Tincati, Eccles-James, Cappione, Ndhlovu, Koth, Nixon: "A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males." dans: PLoS ONE, Vol. 5, Issue 11, pp. e15412, (2011) (PubMed).

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: IL6

ID gène: 3569

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome