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CD4 anticorps (N-Term)

CD4 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p) Hôte: Souris Monoclonal 9H5A8 unconjugated

N° du produit ABIN6990372

Fiche de données

Antigène Voir toutes CD4 Anticorps

CD4
Épitope
29

16

16

16

16

9

7

6

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reactivité
350

209

120

38

24

22

20

19

15

11

10

10

8

7

7

6

6

6

6

2

2

2

1

1

1

1
Humain, Souris, Rat
Hôte
334

144

119

4

2

1

1
Souris
Anticorps secondaires appropriés
Clonalité
460

138

3
Monoclonal
Conjugué
193

64

55

48

29

15

14

12

12

10

10

9

7

7

7

7

5

5

5

5

5

5

5

5

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1
Cet anticorp CD4 est non-conjugé
Application
478

197

113

92

83

75

63

42

39

37

31

25

17

10

9

8

8

7

6

6

5

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

CD4 Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Immunogène

Mouse monoclonal CD4 antibody was raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.

Clone

9H5A8

Isotype

IgG1

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anti-CD4 (CD4) antibody
CD4 Reactivité: Humain, Souris, Rat, Poulet, Singe, Porc, Chien, Cat, Lapin, Boeuf (Vache), Mouton, Cobaye, Chévre, Cheval, Avian, Âne, Hamster WB Hôte: Chèvre Polyclonal unconjugated

anti-CD4 (CD4) (AA 231-330) antibody
CD4 Reactivité: Humain, Souris, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Hôte: Lapin Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody
CD4 Reactivité: Humain FACS, WB, CyTOF Hôte: Souris Monoclonal MEM-241 unconjugated

anti-CD4 (CD4) (AA 300-400) antibody
CD4 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 Reactivité: Souris FACS, IP, IHC (fro), ICC, Func Hôte: Rat Monoclonal GK1-5 unconjugated

anti-CD4 (CD4) (N-Term) antibody (FITC)
CD4 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-241 FITC

anti-CD4 (CD4) (AA 301-400) antibody
CD4 Reactivité: Humain, Souris, Rat FACS, WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody (PE)
CD4 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-241 PE

anti-CD4 (CD4) antibody (PE)
CD4 Reactivité: Rat FACS Hôte: Souris Monoclonal OX-35 PE

Indications d'application

WB: 0.5-4 μ,g/mL, IHC: 5 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

CD4 Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

CD4 monoclonal antibody can be stored at -20°C, stable for one year.
Antigène

CD4

Autre désignation

CD4 (CD4 Produits)

Synonymes

anticorps cd4, anticorps L3T4, anticorps Ly-4, anticorps CD4mut, anticorps W3/25, anticorps p55, anticorps CD4 molecule, anticorps carcinoembryonic antigen-related cell adhesion molecule 5, anticorps T-cell surface glycoprotein CD4, anticorps CD4 antigen, anticorps Cd4 molecule, anticorps CD4, anticorps LOC100125525, anticorps cd4, anticorps Cd4

Sujet

CD4 Monoclonal Antibody: CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 Molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.

Poids moléculaire

Predicted: 51kD

Observed: 51-57 kD (Post-modyfication: 2-4 N-linked glycosylations) kDa

ID gène

920

NCBI Accession

NP_000607

UniProt

P01730

Pathways

TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events