Angiotensin II Type-1 Receptor anticorps (AA 210-260)

N° du produit ABIN6991186

Détail du produit anti-Angiotensin II Type-1 Receptor anticorps

Antigène: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Épitope: AA 210-260

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin II Type-1 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: AGTR1 Antibody is affinity chromatography purified via peptide column.

Immunogène: AGTR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR1. The immunogen is located within amino acids 210 - 260 of AGTR1.

Isotype: IgG

Information d'application

Indications d'application: AGTR1 antibody can be used for detection of AGTR1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AGTR1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: AGTR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Angiotensin II Type-1 Receptor

Antigène: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Autre désignation: AGTR1 (AGTR1 Produits)

Synonymes: anticorps AG2S, anticorps AGTR1A, anticorps AGTR1B, anticorps AT1, anticorps AT1AR, anticorps AT1B, anticorps AT1BR, anticorps AT1R, anticorps AT2R1, anticorps AT2R1A, anticorps AT2R1B, anticorps HAT1R, anticorps 1810074K20Rik, anticorps AI551199, anticorps AT1a, anticorps Agtr-1a, anticorps Agtr1, anticorps Angtr-1a, anticorps AT1A, anticorps XAT-1, anticorps agtr1-A, anticorps agtr1.2, anticorps AT1-R, anticorps at1, anticorps AGTR1, anticorps Agtr-1b, anticorps Angtr-1b, anticorps agtr1, anticorps agtr1-a, anticorps agtr1-b, anticorps xAT, anticorps angiotensin II receptor type 1, anticorps angiotensin II receptor, type 1a, anticorps angiotensin II receptor type 1 S homeolog, anticorps uncharacterized AGTR1, anticorps angiotensin II receptor, type 1b, anticorps angiotensin II receptor type 1 L homeolog, anticorps AGTR1, anticorps Agtr1a, anticorps agtr1.S, anticorps Agtr1, anticorps Agtr1b, anticorps agtr1.L

Sujet: AGTR1 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.

ID gène: 185

UniProt: P30556

Pathways: Signalistation JAK/STAT, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour