NLRP4 anticorps

N° du produit ABIN7239236

Détail du produit anti-NLRP4 anticorps

Antigène: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human NLRP4

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NLRP4

Antigène: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Autre désignation: NLRP4 (NLRP4 Produits)

Synonymes: anticorps CLR19.5, anticorps CT58, anticorps NALP4, anticorps PAN2, anticorps PYPAF4, anticorps RNH2, anticorps Nalp4, anticorps Nlrp4e, anticorps RGD1563529, anticorps NLR family pyrin domain containing 4, anticorps NLR family, pyrin domain containing 4, anticorps NLRP4, anticorps Nlrp4

Sujet: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes

NCBI Accession: NP_604393

UniProt: Q96MN2

Pathways: Inflammasome