PFKFB3 anticorps
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- Antigène Voir toutes PFKFB3 Anticorps
- PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PFKFB3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Attributs du produit
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogène
- Synthetic peptide of human PFKFB3
- Isotype
- IgG
- Top Product
- Discover our top product PFKFB3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
- Autre désignation
- PFKFB3 (PFKFB3 Produits)
- Synonymes
- anticorps IPFK2, anticorps PFK2, anticorps E330010H22Rik, anticorps iPFK-2, anticorps uPFK-2, anticorps PFKFB3, anticorps zgc:73257, anticorps wu:fc31e01, anticorps 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, anticorps 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 S homeolog, anticorps PFKFB3, anticorps Pfkfb3, anticorps pfkfb3.S, anticorps pfkfb3, anticorps PTRG_09894, anticorps Tsp_06710
- Sujet
- The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
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Observed_MW: Refer to figures
Calculated_MW: 60 kDa
- UniProt
- Q16875
- Pathways
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process
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