PTPRJ anticorps

N° du produit ABIN7255177

Détail du produit anti-PTPRJ anticorps

Antigène: PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRJ est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PTPRJ (NP_002834.3).

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PTPRJ

Antigène: PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))

Autre désignation: PTPRJ (PTPRJ Produits)

Synonymes: anticorps HAAP, anticorps CD148, anticorps DEP1, anticorps HPTPeta, anticorps R-PTP-ETA, anticorps SCC1, anticorps AI450271, anticorps BET, anticorps Byp, anticorps DEP-1, anticorps PTPbeta2, anticorps Ptpb2, anticorps RPTPJ, anticorps Scc-1, anticorps Scc1, anticorps PTPRJ, anticorps acid phosphatase 1, anticorps protein tyrosine phosphatase, receptor type J, anticorps protein tyrosine phosphatase, receptor type, J, anticorps ACP1, anticorps PTPRJ, anticorps Ptprj, anticorps EUBREC_2762

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 260 kDa

Calculated_MW: 57 kDa/145 kDa

ID gène: 5795

UniProt: Q12913

Pathways: EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling