DDIT3 anticorps
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- Antigène Voir toutes DDIT3 Anticorps
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DDIT3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human DDIT3 / CHOP (NP_004074.2).
- Isotype
- IgG
- Top Product
- Discover our top product DDIT3 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))
- Autre désignation
- DDIT3 / CHOP (DDIT3 Produits)
- Synonymes
- anticorps chop, anticorps Xchop, anticorps cebpz, anticorps chop10, anticorps gadd153, anticorps CHOP-10, anticorps CHOP10, anticorps CHOP, anticorps Chop10, anticorps Gadd153, anticorps CEBPZ, anticorps GADD153, anticorps DNA damage inducible transcript 3, anticorps DNA-damage inducible transcript 3, anticorps DNA damage inducible transcript 3 L homeolog, anticorps ddit3, anticorps Ddit3, anticorps DDIT3, anticorps ddit3.L
- Sujet
- This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
- Poids moléculaire
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Observed_MW: 30 kDa
Calculated_MW: 19 kDa/21 kDa
- ID gène
- 1649
- UniProt
- P35638
- Pathways
- Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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