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TNFRSF1B anticorps
TNFRSF1B
Reactivité: Humain, Souris, Rat
IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN7257154
Détail du produit anti-TNFRSF1B anticorps
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Antigène
Voir toutes TNFRSF1B Anticorps
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
Reactivité
Toutes les réactivités sur TNFRSF1B Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur TNFRSF1B Anticorps
Lapin
Clonalité
Toutes les clonalités sur TNFRSF1B Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers TNFRSF1B Anticorps
Cet anticorp TNFRSF1B est non-conjugé
Application
Tous les applications à travers TNFRSF1B Anticorps.
Immunohistochemistry (IHC)
Attributs du produit
Polyclonal Antibody
Purification
Affinity purification
Immunogène
Recombinant fusion protein of human TNFRSF1B (NP_001057.1).
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
IHC 1:50-1:200
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur TNFRSF1B
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Antigène
TNFRSF1B
(Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
Autre désignation
TNFRSF1B (TNFRSF1B Produits )
Synonymes
anticorps CD120b, anticorps TBPII, anticorps TNF-R-II, anticorps TNF-R75, anticorps TNFBR, anticorps TNFR1B, anticorps TNFR2, anticorps TNFR80, anticorps p75, anticorps p75TNFR, anticorps TNF-RII/TNFRSF1B, anticorps TNFR-II, anticorps TNFRSF1B, anticorps TNF-R2, anticorps TNF-alphaR2, anticorps TNFRII, anticorps TNFalpha-R2, anticorps Tnfr-1, anticorps Tnfr2, anticorps rank, anticorps zgc:163064, anticorps TNF receptor superfamily member 1B, anticorps tumor necrosis factor receptor superfamily, member 1b, anticorps tumor necrosis factor receptor superfamily, member 1B, anticorps TNFRSF1B, anticorps Tnfrsf1b, anticorps tnfrsf1b
Sujet
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
ID gène
7133
UniProt
P20333
Pathways
Signalisation NF-kappaB , Apoptose , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Ubiquitin Proteasome Pathway
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