anticorps fb16c04, anticorps wu:fb16c04, anticorps zgc:77714, anticorps MGC68415, anticorps CTDSP2, anticorps OS4, anticorps PSR2, anticorps SCP2, anticorps AI586070, anticorps D10Ertd73e, anticorps OS-4, anticorps CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, anticorps CTD small phosphatase 2 L homeolog, anticorps CTD small phosphatase 2, anticorps ctdsp2, anticorps ctdsp2.L, anticorps CTDSP2, anticorps Ctdsp2
Sujet
Synonyms:NIF2, OS4, SCP2 Background:Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain(CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.