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MSL1 anticorps

MSL1 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7116032
  • Antigène Voir toutes MSL1 Anticorps
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    Reactivité
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp MSL1 est non-conjugé
    Application
    Western Blotting (WB), ELISA
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    male-specific lethal 1 homolog(Drosophila)
    Isotype
    IgG
    Top Product
    Discover our top product MSL1 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
    Autre désignation
    MSL1 (MSL1 Produits)
    Synonymes
    anticorps MSL-1, anticorps hMSL1, anticorps 2810017F12Rik, anticorps 4121402D02Rik, anticorps 4930463F05Rik, anticorps AA682082, anticorps Msl-1, anticorps male specific lethal 1 homolog, anticorps male-specific lethal 1 homolog (Drosophila), anticorps MSL1, anticorps Msl1
    Sujet
    Synonyms:MSL1L1 Background:Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
    Poids moléculaire
    67 kDa
    ID gène
    339287
    UniProt
    Q68DK7
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