PKM anticorps
-
- Antigène Voir toutes PKM Anticorps
- PKM (Pyruvate Kinase M1/2 (PKM))
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PKM est non-conjugé
-
Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- PKM2 pyruvate kinase, muscle
- Isotype
- IgG
- Top Product
- Discover our top product PKM Anticorps primaire
-
-
- Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
-
- Antigène
- PKM (Pyruvate Kinase M1/2 (PKM))
- Autre désignation
- PKM (PKM Produits)
- Synonymes
- anticorps CTHBP, anticorps OIP3, anticorps PK3, anticorps PKM2, anticorps TCB, anticorps THBP1, anticorps AA414905, anticorps AL024370, anticorps AL024424, anticorps Pk-2, anticorps Pk-3, anticorps Pk3, anticorps Pkm2, anticorps PKM12, anticorps CG7070, anticorps Dmel\\CG7070, anticorps PYK, anticorps Pyk, anticorps cb1029, anticorps fj33f03, anticorps pkm2, anticorps pkm2a, anticorps wu:fj33f03, anticorps MGC53388, anticorps PKM, anticorps PK-S, anticorps pk3, anticorps pkm2b, anticorps zgc:92037, anticorps pyruvate kinase M1/2, anticorps pyruvate kinase, muscle, anticorps Pyruvate kinase, anticorps pyruvate kinase M1/2a, anticorps pyruvate kinase PKM, anticorps pyruvate kinase (PK), anticorps pyruvate kinase, anticorps pyruvate kinase M1/2 S homeolog, anticorps pyruvate kinase M1/2b, anticorps PKM, anticorps Pkm, anticorps PyK, anticorps pkma, anticorps pkm, anticorps LOC710798, anticorps pyk, anticorps pk, anticorps LOC100534543, anticorps pkm.S, anticorps pkmb
- Sujet
- Synonyms:OIP3, PK2, PK3, PKM2 Background:Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate(PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
- Poids moléculaire
- 58 kDa
- ID gène
- 5315
- UniProt
- P14618
- Pathways
- L'effet Warburg
-