ZC3HC1 anticorps

N° du produit ABIN7121049

Détail du produit anti-ZC3HC1 anticorps

Antigène: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZC3HC1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: zinc finger, C3HC-type containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur ZC3HC1

Antigène: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Autre désignation: ZC3HC1 (ZC3HC1 Produits)

Synonymes: anticorps 1110054L24Rik, anticorps AU018540, anticorps AU019789, anticorps HSPC216, anticorps Nipa, anticorps NIPA, anticorps RGD1561099, anticorps zinc finger, C3HC type 1, anticorps zinc finger C3HC-type containing 1, anticorps zinc finger, C3HC-type containing 1, anticorps Zc3hc1, anticorps ZC3HC1

Sujet: Synonyms:ZC3HC1, 1110054L24Rik, hNIPA, HSPC216, NIPA Background:Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1(CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

Poids moléculaire: 55 kDa

ID gène: 51530

UniProt: Q86WB0