NAC1 anticorps

N° du produit ABIN7126218

Détail du produit anti-NAC1 anticorps

Antigène: NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NAC1 est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: The BTB (broad-complex, tramtrack and bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homo-oligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.

Réactivité croisée (Details): Human

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human NACC1 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, MCF7 or K562 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur NAC1

Antigène: NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))

Autre désignation: NACC1 (NACC1 Produits)

Synonymes: anticorps BEND8, anticorps BTBD14B, anticorps BTBD30, anticorps NAC-1, anticorps NAC1, anticorps NACC1, anticorps 2010001H03Rik, anticorps 4930511N13Rik, anticorps Btbd14b, anticorps Nac1, anticorps Nac-1, anticorps nucleus accumbens associated 1, anticorps nucleus accumbens associated 1, BEN and BTB (POZ) domain containing, anticorps NACC1, anticorps Nacc1

Sujet: BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, NAC-1, NAC1, Nucleus accumbens-associated protein 1,NACC1 / Nac1 / BTBD14B
Cellular localisation: Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation.

Poids moléculaire: 57kDa

ID gène: 112939, 531614

UniProt: Q96RE7