NR1H2 anticorps

N° du produit ABIN7127043

Détail du produit anti-NR1H2 anticorps

Antigène: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NR1H2 est non-conjugé

Application: ELISA, Coating (Coat)

Specificité: The liver X receptors, LXRA (NR1H3) and LXRB (NR1H2) form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements. LXRB can inhibit proliferation and induce apoptosis of cancer cells.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human NR1H2 (LXRB) protein

Isotype: IgG2

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, SW480 or A549 cells. Liver.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur NR1H2

Antigène: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Autre désignation: NR1H2 (NR1H2 Produits)

Synonymes: anticorps NR1H2, anticorps lxr-b, anticorps lxrb, anticorps ner, anticorps ner-i, anticorps rip15, anticorps unr, anticorps DKFZp468A0622, anticorps AI194859, anticorps LXR, anticorps LXRB, anticorps LXRbeta, anticorps NER1, anticorps OR-1, anticorps RIP15, anticorps UR, anticorps Unr, anticorps Unr2, anticorps LXR-b, anticorps NER, anticorps NER-I, anticorps UNR, anticorps nuclear receptor subfamily 1 group H member 2, anticorps nuclear receptor subfamily 1, group H, member 2, anticorps nuclear receptor subfamily 1 group H member 2 L homeolog, anticorps NR1H2, anticorps nr1h2, anticorps Nr1h2, anticorps nr1h2.L

Sujet: Liver X nuclear receptor beta, Liver X receptor beta, LX receptor beta, LXR beta, LXRB, NER1, Nuclear orphan receptor LXR beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2 (NR1H2), OR-1, Oxysterols receptor LXR-beta, RIP15, Steroid hormone nuclear receptor NER, Ubiquitously-expressed nuclear receptor (UNR),Liver X Receptor beta (LXRB) (Orphan Receptor)
Cellular localisation: Nuclear

Poids moléculaire: 56kDa

ID gène: 7376, 432976

UniProt: P55055

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding