BMPR2 anticorps

N° du produit ABIN7128670

Détail du produit anti-BMPR2 anticorps

Antigène: BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMPR2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human BMPR2

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BMPR2

Antigène: BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Autre désignation: BMPR2 (BMPR2 Produits)

Synonymes: anticorps BMPR-II, anticorps BMPR3, anticorps BMR2, anticorps BRK-3, anticorps PPH1, anticorps T-ALK, anticorps 2610024H22Rik, anticorps AL117858, anticorps AW546137, anticorps BB189135, anticorps BMP-2, anticorps BMPR-2, anticorps BMPRII, anticorps Gm20272, anticorps Bmpr-II, anticorps bmprii, anticorps bone morphogenetic protein receptor type 2, anticorps bone morphogenetic protein receptor, type II b (serine/threonine kinase), anticorps bone morphogenetic protein receptor, type II (serine/threonine kinase), anticorps BMPR2, anticorps bmpr2b, anticorps Bmpr2

Sujet:

Background: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Aliases: BMP type II receptor antibody, BMP type-2 receptor antibody, BMPR 2 antibody, BMPR 3 antibody, BMPR II antibody, BMPR-2 antibody, BMPR-II antibody, Bmpr2 antibody, BMPR2_HUMAN antibody, BMPR3 antibody, BMPRII antibody, BMR 2 antibody, BMR2 antibody, Bone morphogenetic protein receptor type 2 antibody, Bone morphogenetic protein receptor type II antibody, Bone morphogenetic protein receptor type-2 antibody, Bone morphogenic protein receptor type II serine threonine kinase antibody, BRK 3 antibody, BRK3 antibody, PPH 1 antibody, PPH1 antibody, Serine threonine kinase type II activin receptor like kinase antibody, T ALK antibody, TALK antibody, Type II activin receptor like kinase antibody

UniProt: Q13873

Pathways: Growth Factor Binding