MAP2K7 anticorps (pThr275)

N° du produit ABIN7138822

Détail du produit anti-MAP2K7 anticorps

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Épitope: pThr275

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K7 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of threonine 275(A-K-T(p)-R-S) derived from Human MAP2K7.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MAP2K7

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Autre désignation: MAP2K7 (MAP2K7 Produits)

Synonymes: anticorps MAP2K7, anticorps 2, anticorps JNKK, anticorps Jnkk2, anticorps Mapkk7, anticorps Mek7, anticorps Mkk7, anticorps MAPKK7, anticorps MKK7, anticorps PRKMK7, anticorps SAPKK-4, anticorps SAPKK4, anticorps 5930412N11Rik, anticorps JNKK 2, anticorps MAPKK 7, anticorps MEK 7, anticorps Prkmk7, anticorps sek2, anticorps si:ch211-254d18.2, anticorps map2k7-A, anticorps mitogen-activated protein kinase kinase 7, anticorps mitogen activated protein kinase kinase 7, anticorps mitogen-activated protein kinase kinase 7 L homeolog, anticorps MAP2K7, anticorps Map2k7, anticorps map2k7, anticorps map2k7.L

Sujet:

Background:

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

Wu Z.,Mol. Cell. Biol. 17:7407-7416(1997).
Lu X.,J. Biol. Chem. 272:24751-24754(1997).
The MGC Project Team,Genome Res. 14:2121-2127(2004).

Aliases: c-Jun N-terminal kinase kinase 2 antibody, Dual specificity mitogen activated protein kinase kinase 7 antibody, Dual specificity mitogen-activated protein kinase kinase 7 antibody, JNK activating kinase 2 antibody, JNK kinase 2 antibody, JNK-activating kinase 2 antibody, JNKK 2 antibody, Jnkk-2 antibody, Jnkk2 antibody, MAP kinase kinase 7 antibody, MAP2K7 antibody, MAPK/ERK kinase 7 antibody, MAPKK 7 antibody, MAPKK-7 antibody, MAPKK7 antibody, MEK 7 antibody, Mitogen Activated Protein Kinase kinase 7 antibody, MKK 7 antibody, MKK-7 antibody, MKK7 antibody, MP2K7_HUMAN antibody, PRKMK 7 antibody, PRKMK-7 antibody, PRKMK7 antibody, SAPK kinase 4 antibody, SAPKK-4 antibody, SAPKK4 antibody, Sek 2 antibody, Sek-2 antibody, Sek2 antibody, SKK4 antibody, stress-activated protein kinase kinase 4 antibody

UniProt: O14733

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling