FAK anticorps (pTyr576, pTyr577)
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- Antigène Voir toutes FAK (PTK2) Anticorps
- FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
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Épitope
- pTyr576, pTyr577
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FAK est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogène
- Peptide sequence around phosphorylation site of tyrosine 576/tyrosine 577 (S-T-Y(p)-Y(p)-K-A) derived from Human FAK.
- Isotype
- IgG
- Top Product
- Discover our top product PTK2 Anticorps primaire
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- Indications d'application
- WB:1:500-1:1000, IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
- Autre désignation
- PTK2 (PTK2 Produits)
- Synonymes
- anticorps FADK, anticorps FAK, anticorps FAK1, anticorps FRNK, anticorps PPP1R71, anticorps p125FAK, anticorps pp125FAK, anticorps PTK2, anticorps Fadk, anticorps mKIAA4203, anticorps fak, anticorps fak1a, anticorps ptk2, anticorps ptk2a, anticorps wu:fa18c04, anticorps zgc:66114, anticorps CG10023, anticorps CT28129, anticorps DFAK, anticorps DFak, anticorps DFak56, anticorps Dfak, anticorps Dfak56, anticorps DmFAK, anticorps Dmel\\CG10023, anticorps Fak56, anticorps Fak56D, anticorps fak56, anticorps protein tyrosine kinase 2, anticorps protein tyrosine kinase 2 L homeolog, anticorps PTK2 protein tyrosine kinase 2, anticorps protein tyrosine kinase 2ab, anticorps Focal adhesion kinase, anticorps PTK2, anticorps ptk2.L, anticorps Ptk2, anticorps ptk2ab, anticorps Fak
- Sujet
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Background:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Parsons, J.T. et al. (2000) Oncogene 19, 5606-5613
Schaller, M.D. et al. (1994) Mol. Cell. Biol. 14, 1680-1688.
Cobb, B.S. et al. (1994) Mol. Cell. Biol. 14, 147-155.
Chen, H.C. et al. (1996) J. Biol. Chem. 271, 26329-26334.Aliases: FADK 1 antibody, FADK antibody, FAK related non kinase polypeptide antibody, FAK1 antibody, FAK1_HUMAN antibody, Focal adhesion kinase 1 antibody, Focal adhesion Kinase antibody, Focal adhesion kinase isoform FAK Del33 antibody, Focal adhesion kinase related nonkinase antibody, FRNK antibody, p125FAK antibody, pp125FAK antibody, PPP1R71 antibody, Protein phosphatase 1 regulatory subunit 71 antibody, Protein tyrosine kinase 2 antibody, Protein-tyrosine kinase 2 antibody, Ptk2 antibody, PTK2 protein tyrosine kinase 2 antibody
- UniProt
- Q05397
- Pathways
- Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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