ROS1 anticorps (AA 1-320) (Biotin)
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- Antigène Voir toutes ROS1 Anticorps
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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Épitope
- AA 1-320
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Reactivité
- Arabidopsis thaliana
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ROS1 est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Arabidopsis thaliana
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)
- Isotype
- IgG
- Top Product
- Discover our top product ROS1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
- Autre désignation
- ROS1 (ROS1 Produits)
- Synonymes
- anticorps MCF3, anticorps ROS, anticorps c-ros-1, anticorps ROS1C, anticorps Ros-1, anticorps c-ros, anticorps ROS proto-oncogene 1, receptor tyrosine kinase, anticorps ROS proto-oncogene 1 , receptor tyrosine kinase, anticorps Ros1 proto-oncogene, anticorps ROS1, anticorps Ros1
- Sujet
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Background: Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed:25240767). Generates 3\'-phosphor-alpha,beta-unsaturated aldehyde (3\'-PUA) as a primary 5-meC excision intermediate (PubMed:25228464). Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair (PubMed:24155752).
Aliases: ROS1 antibody, DML1 antibody, At2g36490 antibody, F1O11.12 antibody, DNA glycosylase/AP lyase ROS1 antibody, EC 4.2.99.18 antibody, DEMETER-like protein 1 antibody, Protein REPRESSOR OF SILENCING 1 antibody, Protein ROS1 antibody
- UniProt
- Q9SJQ6
- Pathways
- Signalisation RTK
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