ARFGAP1 anticorps (AA 1-220)
Aperçu rapide pour ARFGAP1 anticorps (AA 1-220) (ABIN7143460)
Antigène
Voir toutes ARFGAP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-220
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Fonction
- ARFGAP1 Antibody
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Réactivité croisée
- Souris
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 protein (1-220AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
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Autre désignation
- ARFGAP1
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Sujet
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Background: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle\\\'s fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine .
Aliases: ADP ribosylation factor 1 GTPase activating protein antibody, ADP ribosylation factor GTPase activating protein 1 antibody, ADP-ribosylation factor 1 GTPase-activating protein antibody, ADP-ribosylation factor GTPase-activating protein 1 antibody, ARF GAP 1 antibody, ARF1 directed GTPase activating protein antibody, ARF1 GAP antibody, ARF1-directed GTPase-activating protein antibody, ARF1GAP antibody, ARFG1_HUMAN antibody, Arfgap1 antibody, GAP protein antibody, HRIHFB2281 antibody
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UniProt
- Q8N6T3
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Pathways
- Signalisation p53, ER-Nucleus Signaling, Unfolded Protein Response
Antigène
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