MAPK11 anticorps (pThr180, pTyr182) (HRP)

N° du produit ABIN710585

L’anticorps anti-MAPK11 Polyclonal Lapin est utilisé pour la détection de MAPK11 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC (p) et IHC (fro).

Aperçu rapide pour MAPK11 anticorps (pThr180, pTyr182) (HRP) (ABIN710585)

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK11 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MAPK11 anticorps (HRP)

Épitope: pThr180, pTyr182

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MAPK11 around the phosphorylation site of Thr180+Tyr182

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MAPK11

Antigène: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Autre désignation: MAPK11+

Sujet:

Synonyms: MAPK11phospho T180/Y182, Human p38Beta MAP kinase mRNA complete cds, MAP kinase 11, MAP kinase p38 beta, MAPK 11, Mapk11, Mitogen activated protein kinase 11, Mitogen activated protein kinase p38 2, Mitogen activated protein kinase p38 beta, mitogen-activated protein kinase 11, Mitogen-activated protein kinase p38 beta, MK11_HUMAN, p38 2, p38-2, P38B, p38Beta, P38BETA2, PRKM11, protein kinase mitogen activated 11, SAPK2, SAPK2B, Stress activated protein kinase 2, Stress-activated protein kinase 2.

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK11 is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

ID gène: 5600

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins