PKC alpha anticorps (pSer657, pTyr658) (HRP)
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- Antigène Voir toutes PKC alpha (PKCa) Anticorps
- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
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Épitope
- pSer657, pTyr658
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PKC alpha est conjugé à/à la HRP
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human PRKCA around the phosphorylation site of Ser657+Tyr658
- Isotype
- IgG
- Top Product
- Discover our top product PKCa Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
- Autre désignation
- PRKCA+ (PKCa Produits)
- Synonymes
- anticorps pkc-alpha, anticorps pkcalpha, anticorps im:7139045, anticorps si:dkey-8l19.1, anticorps LOC100219195, anticorps AAG6, anticorps PKC-alpha, anticorps PKCA, anticorps PRKACA, anticorps AI875142, anticorps Pkca, anticorps PKRCA, anticorps protein kinase C alpha, anticorps protein kinase C, alpha L homeolog, anticorps protein kinase C, alpha, anticorps PRKCA, anticorps prkca.L, anticorps prkca, anticorps Prkca
- Sujet
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Synonyms: PRKCAphospho S657/Y658, rotein Kinase C, AAG6, Aging associated gene 6, MGC129900, MGC129901, MGC41878, MGC57564, PKC B, PKC beta, PKC zeta, PKC2, PKCB, PKCC, PKCD, PKCE, PKCG, PRKACA, PRKC A, PRKC G, PRKCA, PRKCB, PRKCB1, PRKCB2, PRKCD, PRKCE, PRKCG, PRKCZ , Protein kinase C alpha, Protein kinase C alpha type, Protein Kinase C, Protein kinase C beta 1, Protein kinase C beta 1 polypeptide, Protein kinase C beta, Protein kinase C beta type, Protein kinase C delta, Protein kinase C epsilon, Protein kinase C gamma, Protein kinase C gamma type, Protein kinase C zeta, SCA14, Spinocerebellar ataxia 14.
Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- ID gène
- 5578
- Pathways
- Signalisation WNT, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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