IWS1 anticorps (AA 570-819)
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- Antigène Tous les produits IWS1
- IWS1 (IWS1 Homolog (IWS1))
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Épitope
- AA 570-819
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IWS1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Protein IWS1 homolog protein (570-819AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- IWS1 (IWS1 Homolog (IWS1))
- Autre désignation
- IWS1 (IWS1 Produits)
- Synonymes
- anticorps 1700069O15Rik, anticorps 3000008H23, anticorps AL117927, anticorps AW214353, anticorps RGD1304762, anticorps IWS1, SUPT6H interacting protein, anticorps IWS1, SUPT6 interacting protein, anticorps IWS1, anticorps Iws1
- Sujet
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Background: Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
Aliases: DKFZp761G0123 antibody, FLJ10006 antibody, FLJ14655 antibody, FLJ32319 antibody, Interacts with Spt6 antibody, iws1 antibody, IWS1 homolog antibody, IWS1-like protein antibody, IWS1_HUMAN antibody, IWS1L antibody, MGC126375 antibody, MGC126376 antibody, OTTHUMP00000162262 antibody, Protein IWS1 homolog antibody
- UniProt
- Q96ST2
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