ITPR2 anticorps

N° du produit ABIN7191144

Détail du produit anti-ITPR2 anticorps

Antigène: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITPR2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human ITPR2

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:10000, IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ITPR2

Antigène: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Autre désignation: ITPR2 (ITPR2 Produits)

Synonymes: anticorps AI649341, anticorps InsP3R-2, anticorps InsP3R-5, anticorps Ip3r2, anticorps Itpr5, anticorps insP3R2, anticorps IP3R2, anticorps inositol 1,4,5-trisphosphate receptor type 2, anticorps inositol 1,4,5-triphosphate receptor 2, anticorps inositol 1,4,5-trisphosphate receptor, type 2, anticorps ITPR2, anticorps Itpr2

Sujet:

Background: Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.

Aliases: 4 antibody, 5-trisphosphate receptor antibody, Inositol 1 4 5 trisphosphate receptor type 2 antibody, Inositol 1,4,5-trisphosphate receptor type 2 antibody, Inositol 145 trisphosphate receptor type 2 antibody, InsP3 R2 antibody, InsP3R2 antibody, IP3 R2 antibody, IP3 receptor antibody, IP3 receptor isoform 2 antibody, IP3R 2 antibody, IP3R2 antibody, ITPR 2 antibody, Itpr2 antibody, ITPR2_HUMAN antibody, Type 2 inositol 1 4 5 trisphosphate receptor antibody, Type 2 inositol 1 antibody, Type 2 inositol 145 trisphosphate receptor antibody, Type 2 InsP3 receptor antibody

UniProt: Q14571

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma